Folic acid+ Pyridoxine+ Doxylamine is a combination medicine comprising three drugs used to provide relief from nausea and vomiting during pregnancy. Doxylamine is an antihistamine that works by inhibiting the action of a chemical messenger (histamine), thereby controlling nausea, vomiting, and dizziness. Pyridoxine (vitamin B6) is a form of vitamin B which possesses anti-nausea properties. Folic acid is also a type of Vitamin B essential to maintain healthy women’s reproductive health. Nausea and vomiting during pregnancy also called morning sickness are common symptoms of pregnancy. It begins during the 6^th week of pregnancy lasting up to the 18^th week. However, few women experience morning sickness throughout their gestation. Morning sickness can lead to loss of electrolytes and weight loss in pregnant women.

Take this medicine as per the dosage and duration prescribed by your doctor. The common side effects of Folic acid+ Pyridoxine+ Doxylamine are dizziness, drowsiness, dry mouth, tiredness, and constipation. These side effects are usually mild to moderate. However, if any of these side effects persist or get severe, inform your doctor immediately. Also, tell your doctor if you are allergic to any of the used drugs or you are suffering from asthma, glaucoma (increased pressure in the eye), stomach ulcer, blockage in the stomach and small intestine, blockage in the bladder, and vitamin B12 deficiency. Breastfeeding women and children should not consume this medicine as it can have negative implications.

Nausea and Vomiting in Pregnancy

The Folic acid + Pyridoxine + Doxylamine tablets are a potent medicine capable of inducing a wide range of side effects. The side effects are mild to moderate and only last for a few days. However, if the side effects persist or get severe, consult your doctor immediately. The list of side effects is given below:

• Drowsiness
• Dizziness
• Tiredness
• Dry mouth
• Constipation

Drug Interaction

When two or more drugs are taken simultaneously, unpleasant effects can be noticed. This can also lower the efficacy of medicines taken. The drugs can similarly interact with certain food items and beverages. The medicines can also show undesirable effects if a person is suffering from certain health conditions.

Interaction with Medicines:

• Blood thinners
• Monoamine oxidase inhibitors (selegiline, rasagiline, tranylcypromine, etc.)
• Sleeping pills (zolpidem, alprazolam, triazolam, etc.)
• Pain medicines (morphine and methadone, etc.)
• Cough or cold medicines (brompheniramine, chlorpheniramine, diphenhydramine, etc.)

Interaction with Food Items:

• Avoid alcohol as Folic acid + Pyridoxine + Doxylamine tablets cause’ drowsiness.
• Do not consume food rich in folic acid.

Interaction with Diseases:

• Asthma
• Glaucoma (increased pressure in the eye)
• Stomach ulcer
• Blockage in the stomach and small intestine
• Blockage in the bladder
• Vitamin B12 deficiency

Precautions and Warnings

1. Avoid consuming greasy or oily food that causes nausea or vomiting.
2. The medicine is not suitable for usage by children and breastfeeding mothers.
3. Do not take vitamin B supplementation in any form such as diet, multivitamins, or other supplements.
4. Do not consume alcohol when taking Folic acid + Pyridoxine + Doxylamine tablets as they cause drowsiness which can lead to undesirable consequences.
5. Avoid driving or performing any mental activity that requires your attention, as the medicine causes sleepiness.
6. Store the tablets in a cool and dry place away from direct sunlight.
7. Keep the tablets away from children and pets. Properly dispose of expired and discarded medicines.

Frequently Asked Questions (FAQs)

1. Can I take FOLIC ACID+PYRIDOXINE+DOXYLAMINE on empty stomach?

It is advised to take DOXYLAMINE+FOLIC ACID+PYRIDOXINE 1 or 2 hours before a meal to prevent nausea and vomiting.

2. Can I take a higher than the recommended dose of this medicine?

No, taking a higher than the recommended dose of Folic acid+ Pyridoxine+ Doxylamine can cause increased side effects.

3. Can I stop taking this medicine if I feel better?

You should not stop taking the medicine even if you feel better as sudden stoppage of this medicine may cause a recurrence of symptoms. So, please consult your doctor before discontinuing the medicine.

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