Sucralfate and Oxethazaine Suspension is primarily used in the treatment of acidity, heartburn, gastritis, and stomach ulcers. This suspension is a combination of two medications, namely Sucralfate and Oxethazaine. This medication works by forming a protective layer in the stomach, shielding it from the acid, and also works by reducing the discomfort caused by the acid in the stomach and the intestine. The stomach is protected from acid by a mucous layer. Sometimes, due to excess acid production, the mucous layer gets eroded, leading to conditions like heartburn and gastritis. 

Sucralfate belongs to the ulcer-protectant class of medication, which works by covering the damaged ulcer tissue in the stomach and protects it from acid or injury to facilitate healing. Whereas Oxethazaine is a local anesthetic that offers a quick numbing effect, which quickly relieves the pain and discomfort associated with ulcers, gastritis, and heartburn. Take it on an empty stomach, at least once or twice a day. Do not take antacid medicines half an hour before or after taking this medicine. 

Mestra Pharma is a leading manufacturer and supplier of Sucralfate and Oxethazaine Suspension, which is marketed under the brand name MESTROX-O SUSP. Associate with Mestra Pharma for PCD Pharma Franchise Business Opportunities. 

What is the Working Mechanism of Sucralfate and Oxethazaine Suspension?

This oral suspension is a combination of an ulcer-protectant and a local anesthetic, which works synergistically to provide relief from heartburn, gastritis, acidity, and intestinal ulcers. The working mechanism of this combination suspension has been discussed as follows: 

Sucralfate- It is an ulcer-protectant, which forms a viscous, protective coating over ulcers and eroded stomach linings, acting as a physical barrier against gastric acid, bile, and pepsin. This action promotes the natural healing process of the stomach lining. Additionally, it selectively adheres to damaged ulcer tissue in the stomach and intestines. Along with this, Sucralfate also stimulates prostaglandin production, enhances mucus secretion, which collectively contribute to mucosal defense and repair.

Oxethazaine- It is an anesthetic that works by blocking the nerve signals in the mouth, mucous membrane, and esophagus. This results in numbing these areas, and hence relieving the pain and discomfort easily associated with acid reflux or ulcers.

Medical Benefits of Using Sucralfate and Oxethazaine Suspension

The Medical Benefits of Using Sucralfate and Oxethazaine Suspension have been mentioned as follows:

• Provides effective relief from gastric pain, heartburn, and acidity.
• Promotes healing of stomach and duodenal ulcers.
• Reduces inflammation and protects the gastrointestinal lining.
• Helps manage symptoms of gastritis and acid peptic disorders.
• It is also highly effective in managing acid reflux and severe heartburn.

What are the Possible Side Effects of Using Sucralfate and Oxethazaine Suspension? 

The Sucralfate and Oxethazaine Suspension may cause some possible side effects. If these side effects persist, immediately consult your doctor or healthcare provider. 

A list of Side Effects has been mentioned as follows:

• Constipation
• Dry mouth
• Nausea
• Upset stomach
• Flatulence
• Dizziness
• Headache

General Safety and Precautions 

Some Precautions and safety measures have to be followed while using Sucralfate and Oxethazaine Suspension. Disclose your previous or recent health issues to your healthcare provider.

A list of precautions has been mentioned as follows:

• If you’re pregnant or breastfeeding, avoid using this medication, or use it under a healthcare prescription.
• Patients with kidney disease should exercise caution while taking Sucralfate and Oxethazaine Suspension.
• This combination may cause drowsiness or dizziness. Avoid driving and the use of heavy machinery.
• Disclose any known allergies to sucralfate, oxethazaine, or similar medications. 

Storage Instruction for Sucralfate and Oxethazaine Suspension

Follow the instructions mentioned as follows: 

• Store it in a cool, dry place, below 25°C.
• Avoid freezing it. 
• Keep it away from the sunlight. 
• Keep it out of reach of children.
• Shake it well before use.