Aceclofenac i.p. 50mg + paracetamol i.p. 125mg Suspension – The two-ingredient pain-relief medication is used to relieve pain, reduce inflammation, and lower fever, particularly in children. It acts by blocking chemical messengers, causing pain and swelling. 

The formulation is also helpful in conditions such as headaches, toothaches, ear pain, and musculoskeletal pain.

It is commonly used as a pediatric painkiller and anti-inflammatory syrup. The suspension provides a dual-action effect by combining the anti-inflammatory properties of Aceclofenac with the analgesic efficacy of paracetamol. Together, they offer rapid relief as compared to the drug alone.

Mestra Pharma produces and markets this suspension under the brand name AFEC-P SUS. It is an Ahmedabad-based company that has expertise in manufacturing a wide range of pharma products. The company is a well-known PCD Pharma Franchise company and a third-party manufacturer.

Mechanism of Aceclofenac and Paracetamol Suspension

Aceclofenac- It works by blocking cyclooxygenase enzymes and stopping the production of Prostaglandins, which are responsible for inflammation, swelling, and pain. It also helps to decrease the production of reactive oxygen species and inflammatory cytokines like TNF and 1L-1beta.

Paracetamol- It works in the brain and blocks pain signals. It has limited inflammatory action but is highly effective in reducing fever and managing pain.  

Uses of Aceclofenac and Paracetamol Suspension

The key uses of the suspension are

• Relieves various types of pain, including dental pain, headaches, muscle pain, and gynecological pain.
• Reduces pain and swelling in joints, muscles, tendons, and bones. 
• Used to alleviate symptoms of fever.
• Can be used for pain and swelling related to dental procedures or minor injuries.

Side Effects of Aceclofenac and Paracetamol Suspension

The use of this medication can sometimes cause mild side effects, especially in sensitive children. These effects are generally manageable when the medicine is taken as prescribed.

• Nausea
• Heartburn
• Increased liver enzymes
• Dizziness
• Rashes 

Precautions for Aceclofenac and Paracetamol Suspension

Acelofenac and Paracetamol is a combined painkiller used for fever and inflammation in children. While this medication is widely used, it’s very important to use it according to medical recommendations. Awareness of safety measures plays an important role in achieving good results.

• Consult with your doctor in advance if you have a medical history of heart, kidney, or liver disease, stomach ulcers, asthma, or blood-clotting issues.
• Avoid using the suspension if you are allergic to NSAIDs, aceclofenac, and paracetamol.
• Do not consume alcohol while taking this medication, as alcohol can cause side effects like stomach bleeding and dizziness.
• It is not recommended for breastfeeding or pregnant women as the suspension may affect the baby.
• Do not take other medications with this suspension without asking the doctor, as drugs may interact.

Dosage- Take the medication with food to minimize stomach discomfort. Do not exceed the prescribed dose, as paracetamol can cause liver damage. 

Frequently Asked Questions (FAQs)

Q1- Are Aceclofenac and Paracetamol more effective than Ibuprofen?

A- The choice depends upon the type of pain. For long-term pain like joint pain or muscle pain, the combination of Aceclofenac and Paracetamol is more effective.

Q2- For how long can I give Aceclofenac and Paracetamol suspension to treat symptoms of fever?

A- The appropriate dosage is directed by a physician based on the specific situation.

Q3- Does Aceclofenac and Paracetamol suspension cause stomach pain?

A- Take the medication with food, or after food, to avoid the risk of stomach pain.

Q4- Can I use Aceclofenac and Paracetamol suspension if my child has pain in the teeth?

A- Do not use this suspension without consulting a pediatrician or dentist.

Q5- Does Aceclofenac and Paracetamol suspension make children feel sleepy?

A- Yes, the combination medication makes children feel sleepy.

Q6- Is Aceclofenac and Paracetamol suspension suitable to give for vaccination fever?

A- The suspension is not generally recommended for vaccination fever.

Q7- Are there any storage instructions for Aceclofenac and Paracetamol suspension?

A- Keep in a dry location away from direct sunlight and extra moisture.