Cefexime and Ofloxacin Tablet is a combination of two antibiotics, namely Cefexime and Ofloxacin, commonly prescribed to treat bacterial infections. This medication offers effective relief from a wide range of bacterial infections, such as respiratory tract infections, urinary tract infections, typhoid, and gastrointestinal infections. Apart, it works strongly towards typhoid fever and sexually transmitted diseases like chlamydia and gonorrhoea. Cefexime belongs to the drug class called Cephalosporin, which works by preventing the formation of the bacterial cell wall,  essential for the survival of the bacteria in the human body. 

Whereas, Ofloxacin belongs to the fluoroquinolone class of antibiotics, offering a broad spectrum of antibacterial activity. Bacteria are tiny single-celled organisms. Harmful bacteria cause bacterial infection by multiplying and triggering an immune response. Cefixime and ofloxacin, a broad-range antibiotic, work against a wide range of both gram-positive and gram-negative bacteria. 

Mestra Pharma is a leading manufacturer and supplier of Cefexime and Ofloxacin Tablets, sold under the brand name CEFEST-O. With their state-of-the-art manufacturing facilities, they ensure the quality, safety, efficacy, and affordability of their products. Partner with Mestra Pharma for PCD Pharma Business Opportunities.

Mode of Action of Cefexime and Ofloxacin Tablet 

The mode of Action of Cefexime and Ofloxacin Tablet has been discussed as follows: 

Cefexime, being a third-generation Cephalosporin antibiotic, binds to penicillin-binding proteins, which are essential enzymes for the final step of peptidoglycan cross-linking, providing rigidity to the bacterial cell wall. Cefexime inhibits the PBPs, hence preventing the formation of a proper cell wall. Thus, without a stable cell wall, the bacterial cell becomes weak, ruptures, and ultimately dies. 

Ofloxacin, Ofloxacin enters the bacterial cell and inhibits two key enzymes, DNA Gyrase, responsible for supercoiling DNA, and Topoisomerase IV, essential for separating replicated DNA strands into daughter cells. By blocking these enzymes, Ofloxacin prevents bacteria from replicating and repairing their DNA. It results in the inhibition of bacterial growth and eventual death of the bacteria. 

Together, they broaden the spectrum of activity and reduce the risk of bacteria developing resistance.

What Are The Uses of Cefexime and Ofloxacin Tablets? 

Both Cefexime and Ofloxacin Tablets fall under the category of Antibiotics. Providing an effective treatment for infections of the urinary tract, respiratory system, gastrointestinal tract, reproductive organs, skin, STDs, and post-surgical infections. 

Mentioned below are the uses of Cefexime and Ofloxacin Tablets, as follows: 

1. Effectively treats infections of the urinary tract by eliminating infection-causing bacteria in the bladder, urethra, and kidneys. 
2. Prevents or treats bacterial growth in surgical wounds by controlling the pus, fever, and swelling, and healing tissues.
3. It also treats and manages gastrointestinal infections such as typhoid fever, infectious diarrhea, and dysentery. 
4. Highly effective against Sexually transmitted infections like gonorrhea.
5. Used to treat Intra-abdominal infections within the abdominal cavity.
6. Cefexime and Ofloxacin Tablets are used to treat Nosocomial infections and prevent hospital-acquired infections caused by resistant bacteria.

Possible Side Effects Caused by Cefexime and Ofloxacin Tablets

This combination therapy is generally well tolerated but can cause mild to moderate reactions. Immediately consult your healthcare provider in case you feel discomfort. 

A list of common side effects has been highlighted below: 

• Diarrhoea
• Nausea
• Loose stools
• Abdominal pain
• Vomiting
• Joint or muscle pain
• Changes in taste or smell

Safety and Precautions

While taking Cefexime and Ofloxacin Tablets, certain safety measures must be followed.

These guidelines help patients avoid harmful drug interactions, allergic reactions, incorrect dosages, and misuse.

• Do not skip any doses and finish the full course of treatment even if you feel better.
• Avoid if allergic to Cephalosporins, Penicillins, or Fluoroquinolones.
• Use only if prescribed; either avoid using it if you’re pregnant or breastfeeding. 
• Take it with food to avoid an upset stomach.
• Inform your doctor immediately if you get a rash, itchy skin, swelling of the face, or difficulty in breathing. 

Direction of Use for Cefexime and Ofloxacin Tablets

Follow the instructions below for the usage of Cefexime and Ofloxacin Tablets, as follows: 

1. Take the medicine exactly as prescribed by your doctor.
2. Swallow the tablet whole with a full glass of water.
3. Take it after meals to reduce the risk of stomach upset.
4. Do not crush, break, or chew the tablet.

Frequently Asked Questions (FAQ’s)

1: Are there drug interactions?

Yes. Inform your doctor if you are taking blood thinners (like warfarin), antacids, iron supplements, or other antibiotics.

2: What should I do if I miss a dose?

Take it as soon as you remember. If it’s almost time for the next dose, skip the missed dose—do not double-dose.

3: Can it be used for viral infections like cold or flu?

No. Antibiotics are ineffective against viral infections.

4: Can I stop taking the tablets once I feel better?

No. Complete the full prescribed course to prevent relapse or antibiotic resistance.