Povidone- Iodine 5.0 % Ointment – The medication is used to prevent and treat skin infections in minor cuts, scrapes, burns, and surgical sites. It releases iodine to kill bacteria, viruses, fungi, and protozoa. Povidone-Iodine comes in various formulations such as solution, gel, and ointment, for wound care and surgical preparation. 

It is an antiseptic and disinfectant agent. Povidone-Iodine is a stable complex of iodine and polyvinylpyrrolidone made to deliver effective antiseptic action. The medication works by slow release of iodine, which kills or prevents the growth of microorganisms. Apply the ointment to clean skin. Daily application of the ointment will give you the best results. Do not use the medication more than you need, as it will not give you a faster recovery; instead may cause some side effects. 

How does Povidone-Iodine Ointment work?

Povidone-Iodine works as an antiseptic by slowly releasing potent, free iodine when applied to the skin. Polyvinylpyrrolidone acts as a carrier that holds onto the Iodine(I2). When the solution comes in contact with skin, this complex slowly releases free Iodine over time. This released iodine quickly penetrates into the microbial cells. Within the cell, Iodine oxidizes and iodinates crucial components, including cell membranes, RNA/DNA, and proteins. This disrupts all the essential cellular functions, leading to death of microorganisms.

Side Effects Of Povidone-Iodine Ointment

The following are the possible side effects of Povidine-Iodine Ointment. The reactions are usually temporary but depend on skin sensitivity, frequency of application, and duration of use. 

• Skin Irritation
• Redness
• Dryness or burning sensation
• Allergic reactions, such as swelling
• Itching at the application site
• Peeling Skin
• Temporary brown staining of the skin

Precautions Of Povidone-Iodine Ointment

Certain precautions need to be followed while using Povidone-Iodine Ointment to ensure safety and efficacy. Medical advice from a doctor is necessary to know how long and for how much time it should be applied.

• Do not swallow or use it in the mouth, eyes, or nose unless you are using a mouthwash formulation as prescribed by your doctor.
• Do not use the ointment for more than one week without discussing it with a healthcare professional.
• If you have thyroid or kidney problems or are taking medicines containing lithium, then take advice from your doctor before consuming the tablets, as iodine absorption can interfere with thyroid function.
• The medication is not recommended for women who are pregnant or planning to become pregnant.
• Avoid applying the ointment on puncture wounds, animal bites, or severe burns. 

Method of Application of Povidone Iodine Ointment 

• Clean and dry the area where the ointment needs to be applied.
• Allow the solution to dry completely before applying a bandage or dressing. Do not use tight bandages.
• Remove the jewelry before using the ointment, as the solution can cause brown stains on skin and permanent stains on jewelry.
• Fabric stains from the solution can be removed with diluted ammonia and water.